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Pharmacology for nursing care /

by Lehne, Richard A [author].
Material type: materialTypeLabelBookPublisher: Canada: Elsevier; 2007Edition: 6th ed.Description: xxii, 1,354 p. : col, ill ; 29 cm + 1 CD-ROM (4 3/4 in.).ISBN: 1416025529; 9781416025528.Subject(s): Pharmacology | Nursing | Pharmacology | Drug Therapy | Nurses' Instruction
Contents:
Introduction -- Orientation to pharmacology -- Four basic terms -- Properties of an ideal drug -- The therapeutic objective -- Factors that determine the intensity of drug responses -- Application of pharmacology in nursing practice -- Evolution of nursing responsibilities regarding drugs -- Application of pharmacology in patient care -- Application of pharmacology in patient education -- Application of the nursing process in drug therapy -- Drug regulation, development, names, and information -- Landmark drug legislation -- New drug development -- Drug names -- Over-the-counter drugs -- Sources of drug information -- Basic principles of pharmacology -- Pharmacokinetics -- Application of pharmacokinetics in therapeutics -- A note to chemophobes -- Passage of drugs across membranes -- Absorption -- Distribution -- Metabolism-- Excretion -- Time course of drug responses -- Pharmacodynamics -- Dose-response relationships -- Drug-receptor interactions -- Drug responses that do not involve receptors -- Interpatient variability in drug responses -- The therapeutic index -- Drug interactions -- Drug-drug interactions -- Drug-food interactions -- Drug-herb interactions
Adverse drug reactions and medication errors -- Adverse drug reactions -- Medication errors -- Individual variation in drug responses -- Body weight and composition -- Age -- Pathophysiology -- Tolerance -- Placebo effect -- Variability in absorption -- Genetics -- Gender -- Race -- Failure to take medicine as prescribed -- Drug interactions -- Diet
Drug therapy across the lifespan -- Drug therapy during pregnancy and breast-feeding -- Drug therapy during pregnancy : basic considerations -- Drug therapy during pregnancy : teratogenesis -- Drug therapy during breast-feeding -- Drug therapy in pediatric patients -- Pharmacokinetics : neonates and infants -- Pharmacokinetics : children 1 year and older -- Adverse drug reactions -- Dosage determination -- Promoting adherence -- Drug therapy in geriatric patients -- Pharmacokinetic changes in the elderly -- Pharmacodynamic changes in the elderly -- Adverse drug reactions and drug interactions -- Promoting adherence -- Peripheral nervous system drugs -- Introduction -- Basic principles of neuropharmacology -- How neurons regulate physiologic processes -- Basic mechanisms by which neuropharmacologic agents act -- Physiology of the peripheral nervous system -- Divisions of the nervous system -- Overview of autonomic nervous system functions -- Basic mechanisms by which the autonomic nervous system regulates physiologic processes -- Anatomic considerations -- Introduction to transmitters of the peripheral nervous system -- Introduction to receptors of the peripheral nervous system -- Exploring the concept of receptor subtypes -- Locations of receptor subtypes -- Functions of cholinergic and adrenergic receptor subtypes -- receptor specificity of the adrenergic receptor subtypes -- Receptor specificity of the adrenergic transmitters -- Transmitter life cycles
Cholinergic drugs -- Muscarinic agonists and antagonists -- Muscarinic agonists -- Muscarinic antagonists (anticholinergic drugs) -- Cholinesterase inhibitors and their use in myasthenia gravis -- Reversible cholinesterase inhibitors -- "Irreversible" cholinesterase inhibitors -- Myasthenia gravis -- Drugs that block nicotinic cholinergic transmission : neuromuscular blocking agents and ganglionic blocking agents -- Neuromuscular blocking agents -- Ganglionic blocking agents -- Adrenergic drugs -- Adrenergic agonists -- Mechanisms of adrenergic receptor activation -- Overview of the adrenergic agonists -- Therapeutic applications and adverse effects of adrenergic receptor activation -- Properties of representative adrenergic agonists -- Discussion of adrenergic agonists in other chapters -- Adrenergic antagonists -- Alpha-adrenergic antagonists 1 : therapeutic and adverse responses to alpha blockade -- Alpha-adrenergic antagonists 2 : properties of individual alpha blockers -- Indirect-acting antiadrenergic agents -- Adrenergic neuron-blocking agents -- Centrally acting alpha₂ agonists
Central nervous system drugs -- Introduction to central nervous system pharmacology -- Transmitters of the CNS -- The blood-brain barrier -- How do CNS drugs produce therapeutic effects? -- Adaptation of the CNS to prolonged drug exposure -- Development of new psychotherapeutic drugs -- Approaching the study of CNS drugs -- Drugs for neurodegenerative disorders -- Drugs for Parkinson's disease -- Pathophysiology of Parkinson's disease -- Overview of drug therapy -- Pharmacology of the drugs used for Parkinson's disease -- Alzheimer's disease -- Pathophysiology of Alzheimer's disease -- Risk factors, symptoms, and diagnosis -- Drug therapy -- Drugs for multiple sclerosis -- Overview of MS and its treatment -- Disease modifying drugs 1 : immunomodulators -- Disease modifying drugs 2 : immunosuppressants -- Drugs used to manage MS symptoms -- Neurologic drugs -- Drugs for epilepsy -- Seizure generation-- Types of seizures -- How antiepileptic drugs work -- Basic therapeutic considerations -- Classification of antiepileptic drugs -- Traditional antiepileptic drugs -- Newer antiepileptic drugs -- Management of epilepsy during pregnancy -- Management of generalized convulsive status epilepticus
Drugs for muscle spasm and spasticity -- Seizure generation -- Types of seizures -- How antiepileptic drugs work -- Basic therapeutic considerations-- Classification of antiepileptic drugs -- Traditional antiepileptic drugs -- Newer antiepileptic drugs -- Management of epilepsy during pregnancy -- Management of generalized convulsive status epilepticus -- Drugs for pain -- Drug therapy of muscle spasm : centrally acting muscle relaxants -- Drugs for spasticity -- Local anesthetics -- Basic pharmacology of the local anesthetics -- Properties of individual local anesthetics -- Clinical use of local anesthetics -- General anesthetics -- Basic pharmacology of the inhalation anesthetics -- Properties of individual inhalation anesthetics -- Intravenous anesthetics -- Opioid (narcotic) analgesics, opioid antagonists, and nonopioid centrally acting analgesics --Introduction to the opioids -- Basic pharmacology of the opioids -- Clinical use of opioids -- Opioid antagonists -- Nonopioid centrally acting analgesics -- Pain management in patients with cancer -- Pathophysiology of pain -- Management strategy -- Assessment and ongoing evaluation -- Drug therapy -- Nondrug therapy -- Pain management in special populations -- patient education -- JCAHO pain management standards
Drugs for headache -- Migraine headache 1 : characteristics and overview of treatment -- Migraine headache 2 : abortive therapy -- Migraine headache 3 : preventive therapy -- Cluster headaches -- Tension[type headache -- Psychotherapeutic drugs -- Antipsychotic agents and their use in schizophrenia -- Schizophrenia : clinical presentation and etiology-- Conventional antipsychotic agents 1 : group properties -- Conventional antipsychotic agents 2 : properties of individual agents -- Atypical antipsychotic agents -- Management of schizophrenia -- Antidepressants -- Major depression : clinical features, pathogenesis, and treatment modalities -- Suicide risk with antidepressant drugs -- Tricyclic antidepressants -- Selective serotonin reuptake inhibitors (SSRIs) -- Serotonin/norepinephrine reuptake inhibitors (S/NRIs) -- Monoamine oxidase inhibitors (MAOIs) -- Atypical antidepressants -- Electroconvulsive therapy -- Vagus nerve stimulation -- Drugs for bipolar disorder -- Characteristics of bipolar disorder -- Treatment of bipolar disorder -- Mood-stabilizing drugs -- Antipsychotic drugs -- Sedative-hypnotic drugs -- Benzodiazepines -- Benzodiazepine-like drugs -- Ramelteon : a melatonin agonist -- Barbiturates -- Miscellaneous sedative-hypnotics -- Management of transient insomnia
Management of anxiety disorders -- Generalization anxiety disorder -- Panic disorder -- Obsessive-compulsive disorder -- Social anxiety disorder (social phobia) -- Post-traumatic stress disorder -- Central nervous system stimulants and attention-deficit/hyperactivity disorder -- Amphetamines -- Methylphenidate and dexmethylphenidate -- Methylxanthines -- Miscellaneous CNS stimulants -- Attention-deficit/hyperactivity disorder -- Drug abuse -- Drug abuse 1 : basic considerations -- Definitions -- Diagnostic criteria for substance abuse and substance dependence -- Factors that contribute to drug abuse -- neurobiology of addiction -- Principles of addiction treatment -- The Controlled Substance Act -- Drug abuse 2 : alcohol -- Basic pharmacology of alcohol -- Alcohol abuse -- Drugs employed in alcohol abuse treatment -- Drug abuse 3 : major drugs of abuse (other than alcohol) -- Heroin and other opioids -- General CNS depressants -- Psychostimulants -- Marijuana and related preparations -- Psychedelics -- 3, 4-methylenedioxymethamphetamine (MDMA, Ecstasy) -- Phencyclidine -- Inhalants -- Nicotine and smoking -- Anabolic steroids
Drugs that affect fluid and electrolyte balance -- Diuretics -- Review of renal anatomy and physiology -- Introduction to diuretics -- High-ceiling (loop) diuretics -- Thiazides and related diuretics -- Thiazides and related diuretics -- Potassium-sparing diuretics -- Osmotic diuretics -- Agents affecting the volume and ion content of body fluids -- Disorders of fluid volume and osmolality -- Acid-base disturbances -- Potassium imbalances -- Magnesium imbalances -- Drugs that affect the heart, blood vessels, and blood -- Review of hemodynamics -- Overview of the circulatory system -- Regulation of cardiac output -- Regulation of arterial pressure -- Drugs acting on the renin-angiotensin-aldosterone system -- Physiology of the renin-angiotensin-aldosterone system -- Angiotensin-converting enzyme inhibitors -- Angiotensin 2 receptor blockers -- Aldosterone antagonists -- Calcium channel blockers -- Calcium channels : physiologic functions and consequences of blockade -- Calcium channel blockers : classification and sites of action -- Verapamil and diltiazem : agents that act on vascular smooth muscle and the heart -- Dihydropyridines : agents that act mainly on vascular smooth muscle
Vasodilators -- Basic concepts invasodilator pharmacology -- Pharmacology of individual vasodilators -- Drugs for hypertension -- Classification of blood pressure -- Types of hypertension -- Consequences of hypertension -- Management of chronic hypertension 1 : basic considerations -- Management of chronic hypertension 2 : lifestyle modifications -- Management of chronic hypertension 3 : drug therapy -- Drugs for hypertensive emergencies -- Drugs for hypertensive disorders of pregnancy -- Drugs for heart failure -- Pathophysiology of heart failure -- Overview of drugs used to treat heart failure -- Cardiac (digitalis) glycosides -- Management of heart failure -- Antidysrhythmic drugs -- Electrical properties of the heart -- Generation of dysrhythmias -- Classification of antidysrhythmic drugs -- Prodysrhythmic effects of antidysrhythmic drugs -- Overview of common dysrhythmias and their treatment -- Class 1 : sodium channel blockers -- Class 2 : beta blockers -- Class 3 : potassium channel blockers (drugs that delay repolarization) -- Class 4 : calcium channel blockers -- Other antidysrhythmic drugs -- Principles of antidysrhythmic drug therapy -- Nondrug treatment of dysrhythmias
Prophylaxis of coronary heart disease : drugs that lower LDL cholesterol levels -- Cholesterol -- Plasma lipoproteins -- Role of LDL cholesterol in atherosclerosis -- Detection, evaluation, and treatment of high cholesterol : recommendations from ATP 3 -- Drugs and other products used to alter plasma lipid levels -- Drugs for angina pectoris -- Determinants of cardiac oxygen demand and oxygen supply -- Angina pectoris : pathophysiology and treatment strategy -- Organic nitrates -- Beta blockers -- Calcium channel blockers -- Revascularization therapy : CABG and PCI -- Summary of treatment measures -- Anticoagulant, antiplatelet, and thrombolytic drugs -- Physiology and pathophysiology of coagulation -- Overview of drugs used to treat thromboembolic disorders -- Parenteral anticoagulants 1 : heparin and related drugs -- Parenteral anticoagulants 2 : direct thrombin inhibitors -- Warfarin, and oral anticoagulant -- Antiplatelet drugs -- Thrombolytic drugs -- Management of ST-elevation myocardial infarction -- Pathophysiology of STEMI -- Diagnosis of STEMI -- Management of STEMI -- Complications of STEMI -- Secondary prevention of STEMI -- Drugs for hemophilia -- Basic considerations -- Preparations used to treat hemophilia -- Drugs for deficiency anemias -- Red blood cell development -- Iron deficiency -- Vitamin B₁₂ deficiency -- Folic acid defficiency -- Hematopoietic growth factors -- Erythropoietic growth factors -- Luekopoietic growth factors -- Thrombopoietic growth factor
Drugs for endocrine disorders -- Drugs for diabetes mellitus -- Diabetes mellitus : overview of the disease and its treatment -- Insulin 1 : physiology-- Insulin 2 : preparations and administration -- Insulin 3 : therapeutic use -- Oral hypoglycemics for type 2 diabetes -- New injectable drugs for diabetes -- Diabetic ketoacidosis -- Glucagon for insulin overdose -- Drugs for thyroid disorders -- Thyroid physiology -- Thyroid function tests -- Thyroid pathophysiology -- Thyroid hormone preparations for hypothyroidism -- Drugs for hyperthyroidism -- Drugs related to hypothalamic and pituitary function -- Overview of hypothalamic and pituitary endocrinology -- Growth hormone -- Prolactin -- Thyrotropin -- Corticotropin -- Gonadotropins -- Antidiuretic hormone -- Oxytoxin -- Drugs related to hypothalamic function -- Drugs for disorders of the adrenal cortex -- Physiology of the adrenocortical hormones -- Pathophysiology of the adrenocortical hormones -- Agents for replacement therapy in adrenocortical insufficiency -- Agents for diagnostic testing of adrenocortical function -- Inhibitors of corticosteroid synthesis
Women's health -- Estrogens and progestins : basic pharmacology and noncontraceptive applications -- The menstrual cycle -- Estrogens -- Selective estrogen receptor modulators (SERMs) -- Progestins -- Menopausal hormone therapy -- Birth control -- Effectiveness and safety of birth control methods -- Selecting a birth control method -- Oral contraceptives -- Combination contraceptives with novel delivery systems -- Long-acting contraceptives -- Spermicides -- Barrier devices -- Drugs for medical abortion -- Drug therapy of infertility -- Infertility : causes and treatment strategies -- Drugs used to treat female infertility -- Drugs that affect uterine function -- Uterine relaxants (tocolytics) and their use in preterm labor -- Uterine stimulants (oxytocicis) -- Drugs used to promote cervical ripening -- Men's health -- Androgens -- Testosterone -- Clinical pharmacology of the androgens -- Androgen (anabolic steroid) abuse by athletes -- Drugs for erectile dysfunction and benign prostatic hyperplasia -- Erectile dysfunction -- Benign prostatic hyperplasia
Anti-inflammartory, antiallergic, and immunologic drugs -- Review of the immune system -- Introduction to the immune system -- Antibody-mediated (humoral) immunity -- Cell-mediated immunity -- Childhood immunization -- General considerations -- Target diseases -- Specific vaccines and toxoids -- Immunosuppressants -- Calcineurin inhibitors -- Sirlimus -- Glucocorticoids -- Cytotoxic drugs -- Antibodies -- Antihistamines -- Histamine -- The two types of antihistamines : H₁ antagonists and H₂ antagonists -- H₁ antagonists 1 : basic pharmacology -- H₁ antagonists 2 : preparations -- Cyclooxygenase inhibitors : nonsteroidal anti-inflammatory drugs and acetaminophen -- Mechanism of action -- Classificationod cyclooxygenase inhibitors -- First-generation NSAIDs -- Second-generation NSAIDs (COX-2 inhibitors, coxibs) -- Acetaminophen -- Glucocorticoids in nonendocrine diseases -- Review of glucocorticoid physiology -- Pharmacology of the glucocorticoids -- Drugs for bone and joint disorders -- Drug therapy of rheumatoid arthritis and gout -- Drug therapy of rheumatoid arthritis -- Drug therapy of gout -- Drugs affecting calcium levels and bone mineralization -- Calcium physiology -- Calcium-related pathophysiology-- Drugs for disorders involving calcium -- Osteoporosis
Respiratory tract drugs -- Drugs for asthma -- Pathophysiology of asthma -- Overview of drugs for asthma -- Administration of drugs by inhalation -- Beta₂-adrenergic agonists -- Glucocorticoids -- Glucocorticoid/Beta₂ agonist combination -- Cromolyn -- Nedocromil -- Methylxanthines -- Anticholinergic drugs -- Leukotriene modifiers -- Omalizumab -- Management of asthma -- Drugs for allergic rhinitis, cough, and colds -- Drugs for allergic rhinitis -- Drugs for cough -- Cold remedies : combination preparations -- Gastrointestinal drugs -- Drugs for peptic ulcer disease -- Laxatives -- Other gastrointestinal drugs -- Antiemetics -- Drugs for motion sickness -- Antidiarrheal agents -- Drugs for irritable bowel syndrome -- Drugs for inflammatory bowel disease -- Prokinetic agents -- Palifermin -- Pancreatic enzymes -- Drugs used to dissolve gallstones -- Anorectal preparations -- Nutrition -- Vitamins -- General considerations -- Fat-soluble vitamins -- Water-soluble vitamins -- Enteral and parenteral nutrition -- Enteral nutritional therapy -- Parenteral nutritional therapy -- Drugs for obesity -- Assessment of obesity-related health risk -- Overview of obesity treatment -- Weight-loss drugs approved for long-term use -- Miscellaneous appetite suppressants -- Investigational weight-loss drugs -- Calorie-saving foods
Chemotherapy of infectious diseases -- Basic principles of antimicrobial therapy -- Selective toxicity -- Classification of antimicrobial drugs -- Acquired resistance to antimicrobial drugs -- Selection of antibiotics -- Host factors that modify drug choice, route of administration, or dosage -- Dosage size and duration of treatment -- Therapy with antibiotic combinations -- Prophylactic use of antimicrobial drugs -- Misuses of antimicrobial drugs -- Monitoring antimicrobial therapy -- Drugs that weaken the bacterial cell wall 1 : penicillins -- Introduction to the penicillins -- Properties of individual penicillins -- Drugs that weaken the bacterial cell wall 2 : cephalosporins, carbapenems, vancomycin, aztreonam, teicoplanin, and fosfomycin -- Cephalosporins -- Carbapenems -- Other inhibitors of cell wall synthesis -- Bacteriostatic inhibitors of protein synthesis : tetracyclines, macrolides and others -- Tetracyclines -- Macrolides -- Other bacteriostatic inhibitors of protein synthesis -- Aminoglycosides : bactericidal inhibitors of protein synthesis -- Basic pharmacology of the aminoglycosides -- Sulfonamides and trimethoprim -- Sulfonamides -- Trimethoprim -- Trimethoprim/sulfamethoxazole -- Drug therapy of urinary tract infections -- Organisms that cause urinary tract infections -- Specific urinary tract infections and their treatment -- Urinary tract antiseptics
Antimycobacterial agents : drugs for tuberculosis, leprosy, and mycobacterium avium complex infection -- Tuberculosis 1 : clinical considerations -- Tuberculosis 2 : pharmacology of individual antituberculosis drugs -- Drugs for leprosy (Hansen's disease) -- Drugs for mycobacterium avium complex infection -- Miscellaneous antibacterial drugs : fluoroquinolones, metronidazole, daptomycin, rifampin, bacitracin, and polymyxins -- Fluoroquinolones -- Additional antibacterial drugs -- Antifungal agents -- Drugs for systemic mycoses -- Drugs for superficial mycoses -- Antiviral agents 1 : drugs for non-HIV viral infections -- Drugs for infection with herpes simplex viruses and varicella-zoster virus -- Drugs for cytomegalovirus infection -- Drugs for hepatitis -- Drugs for influenza -- Drugs for respiratory syncytial virus infection -- Antiviral agents 2 : drugs for HIV infection and related opportunistic infections -- Pathophysiology -- Classification of antiretroviral drugs -- Nucleoside/nucleotide reverse transcriptase inhibitors -- Non-nucleoside reverse transcriptase inhibitors -- Protease inhibitors -- Enfuvirtide, an HIV fusion inhibitor -- Management of HIV infection -- Prophylaxis and treatment of opportunistic infections -- HIV vaccines -- Keeping current
Drug therapy of sexually transmitted diseases -- Chlamydia trachomatis infections -- Gonococcal infections -- Nongonococcal urethritis -- Pelvic inflammatory disease -- Acute epididymitis -- Syphilis -- Acquired immunodeficiency syndrome -- Chancroid -- Trichomoniasis -- Bacterial vaginosis -- Herpes simplex virus infections -- Genital and anal warts (condylomata acuminata) -- Proctitis -- Antiseptics and disinfectants -- General considerations -- Properties of individual antiseptics and disinfectants -- Hand hygiene for healthcare workers -- Chemotherapy of parasitic diseases -- Anthelmintics -- Classification of parasitic worms -- Helminthic infestations -- Drugs of choice for helminthiasis -- Antiprotozoal drugs 1: antimalarial agents -- Life cycle of the malaria parasite -- Types of malaria -- Principles of antimalarial therapy -- Pharmacology of the major antimalarial drugs -- Antiprotozoal drugs 2 : miscellaneous agents -- Protozoal infections -- Drugs of choice for protozoal infections -- Ectoparasiticides -- Ectoparasitic infestations -- Pharmacology of ectoparasiticides
Cancer chemotherapy -- Basic principles of cancer chemotherapy -- What is cancer? -- The growth fraction and its relationship to chemotherapy -- Obstacles to successful chemotherapy -- Strategies for achieving maximum benefits from chemotherapy -- Major toxicities of chemotherapeutic drugs -- Making the decision to treat -- Looking ahead -- Anticancer drugs 1: cytotoxic agents -- Introduction to the cytotoxic anticancer drugs -- Alkylating agents -- Platinum compounds -- Antimetabolites -- Antitumor antibiotics -- Mitotic inhibitors -- Mitotic inhibitors -- Topoisomerase inhibitors -- Miscellaneous cytotoxic drugs -- Anticancer drugs 2 : hormonal agents, biologic response modifiers, and targeted drugs -- Glucocorticoids -- Drugs for prostate cancer -- Drugs for breast cancer -- Biologic response modifiers : immunostimulants -- Targeted drugs -- Additional important drugs -- Drugs for the eye -- Drugs for glaucoma -- Cycloplegics and mydriatics -- Drugs for allergic conjunctivitis -- Drugs for age-related macular degeneration -- Additional ophthalmic drugs
Drugs for the skin -- Anatomy of the skin -- Topical glucocorticoids -- Keratolytic agents -- Acne -- Sunscreens -- Psoriasis -- Other dermatologic drugs -- Drugs for the ear -- Anatomy of the ear -- Otitis media and its management -- Otitis externa and its management -- Miscellaneous noteworthy drugs -- Drugs for pulmonary arterial hypertension -- Drotrecogin Alfa (activated) for severe sepsis -- Drugs for neonatal respiratory distress syndrome -- Drugs for cystic fibrosis -- Drugs for sickle cell anemia -- Drugs for hyperuicemia caused by cancer chemotherapy -- Gamma-hydroxybutyrate for cataplexy in patients with narcolepsy -- Riluzole for amyotrophic lateral sclerosis -- Alternative therapy -- Herbal supplements -- Limited regulation : the Dietary Supplement Health and Education Act -- Adverse interactions with conventional drugs -- Oral formulations -- Standardization of herbal products -- Dosage -- Some commonly used medicinal herbs
Toxicology -- Management of poisoning -- Fundamentals of treatment -- Drugs and procedures used to minimize poison absorption -- Drugs and procedures used for poison removal -- Specific antidotes -- Poison control centers -- Potential weapons of biologic, radiologic, and chemical terrorism -- Bacteria and viruses -- Biotoxins -- Chemical weapons -- Radiologic weapons -- Appendixes -- Adult immunization -- Guide to gender-related drugs -- Pronunciation of generic drug names -- Weights and measures -- Normal laboratory values -- Commonly used abbreviations -- Techniques of drug administration -- Poison Control Centers in the United States -- Canadian drug information -- Major drug classes and their prototypes -- Very new drugs and important new formulations of older drugs
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Item type Current location Call number Copy number Status Notes Date due Barcode
Books Books KAMPALA UNIVERSITY NURSING SCHOOL
General Section
QV4 P45 2007 (Browse shelf) 1 Available AVAILLABLE 2025-4378

Includes bibliographical references and index

[pt]. 1. Introduction -- 1. Orientation to pharmacology -- Four basic terms -- Properties of an ideal drug -- The therapeutic objective -- Factors that determine the intensity of drug responses -- 2. Application of pharmacology in nursing practice -- Evolution of nursing responsibilities regarding drugs -- Application of pharmacology in patient care -- Application of pharmacology in patient education -- Application of the nursing process in drug therapy -- 3. Drug regulation, development, names, and information -- Landmark drug legislation -- New drug development -- Drug names -- Over-the-counter drugs -- Sources of drug information -- [pt]. 2. Basic principles of pharmacology -- 4. Pharmacokinetics -- Application of pharmacokinetics in therapeutics -- A note to chemophobes -- Passage of drugs across membranes -- Absorption -- Distribution -- Metabolism-- Excretion -- Time course of drug responses -- 5. Pharmacodynamics -- Dose-response relationships -- Drug-receptor interactions -- Drug responses that do not involve receptors -- Interpatient variability in drug responses -- The therapeutic index -- 6. Drug interactions -- Drug-drug interactions -- Drug-food interactions -- Drug-herb interactions

7. Adverse drug reactions and medication errors -- Adverse drug reactions -- Medication errors -- 8. Individual variation in drug responses -- Body weight and composition -- Age -- Pathophysiology -- Tolerance -- Placebo effect -- Variability in absorption -- Genetics -- Gender -- Race -- Failure to take medicine as prescribed -- Drug interactions -- Diet

[pt]. 3. Drug therapy across the lifespan -- 9. Drug therapy during pregnancy and breast-feeding -- Drug therapy during pregnancy : basic considerations -- Drug therapy during pregnancy : teratogenesis -- Drug therapy during breast-feeding -- 10. Drug therapy in pediatric patients -- Pharmacokinetics : neonates and infants -- Pharmacokinetics : children 1 year and older -- Adverse drug reactions -- Dosage determination -- Promoting adherence -- 11. Drug therapy in geriatric patients -- Pharmacokinetic changes in the elderly -- Pharmacodynamic changes in the elderly -- Adverse drug reactions and drug interactions -- Promoting adherence -- [pt]. 4. Peripheral nervous system drugs -- Introduction -- 12. Basic principles of neuropharmacology -- How neurons regulate physiologic processes -- Basic mechanisms by which neuropharmacologic agents act -- 13. Physiology of the peripheral nervous system -- Divisions of the nervous system -- Overview of autonomic nervous system functions -- Basic mechanisms by which the autonomic nervous system regulates physiologic processes -- Anatomic considerations -- Introduction to transmitters of the peripheral nervous system -- Introduction to receptors of the peripheral nervous system -- Exploring the concept of receptor subtypes -- Locations of receptor subtypes -- Functions of cholinergic and adrenergic receptor subtypes -- receptor specificity of the adrenergic receptor subtypes -- Receptor specificity of the adrenergic transmitters -- Transmitter life cycles

Cholinergic drugs -- 14. Muscarinic agonists and antagonists -- Muscarinic agonists -- Muscarinic antagonists (anticholinergic drugs) -- 15. Cholinesterase inhibitors and their use in myasthenia gravis -- Reversible cholinesterase inhibitors -- "Irreversible" cholinesterase inhibitors -- Myasthenia gravis -- 16. Drugs that block nicotinic cholinergic transmission : neuromuscular blocking agents and ganglionic blocking agents -- Neuromuscular blocking agents -- Ganglionic blocking agents -- Adrenergic drugs -- 17. Adrenergic agonists -- Mechanisms of adrenergic receptor activation -- Overview of the adrenergic agonists -- Therapeutic applications and adverse effects of adrenergic receptor activation -- Properties of representative adrenergic agonists -- Discussion of adrenergic agonists in other chapters -- 18. Adrenergic antagonists -- Alpha-adrenergic antagonists 1 : therapeutic and adverse responses to alpha blockade -- Alpha-adrenergic antagonists 2 : properties of individual alpha blockers -- 19. Indirect-acting antiadrenergic agents -- Adrenergic neuron-blocking agents -- Centrally acting alpha₂ agonists

[pt]. 5. Central nervous system drugs -- 20. Introduction to central nervous system pharmacology -- Transmitters of the CNS -- The blood-brain barrier -- How do CNS drugs produce therapeutic effects? -- Adaptation of the CNS to prolonged drug exposure -- Development of new psychotherapeutic drugs -- Approaching the study of CNS drugs -- Drugs for neurodegenerative disorders -- 21. Drugs for Parkinson's disease -- Pathophysiology of Parkinson's disease -- Overview of drug therapy -- Pharmacology of the drugs used for Parkinson's disease -- 22. Alzheimer's disease -- Pathophysiology of Alzheimer's disease -- Risk factors, symptoms, and diagnosis -- Drug therapy -- 23. Drugs for multiple sclerosis -- Overview of MS and its treatment -- Disease modifying drugs 1 : immunomodulators -- Disease modifying drugs 2 : immunosuppressants -- Drugs used to manage MS symptoms -- Neurologic drugs -- 24. Drugs for epilepsy -- Seizure generation-- Types of seizures -- How antiepileptic drugs work -- Basic therapeutic considerations -- Classification of antiepileptic drugs -- Traditional antiepileptic drugs -- Newer antiepileptic drugs -- Management of epilepsy during pregnancy -- Management of generalized convulsive status epilepticus

25. Drugs for muscle spasm and spasticity -- Seizure generation -- Types of seizures -- How antiepileptic drugs work -- Basic therapeutic considerations-- Classification of antiepileptic drugs -- Traditional antiepileptic drugs -- Newer antiepileptic drugs -- Management of epilepsy during pregnancy -- Management of generalized convulsive status epilepticus -- Drugs for pain -- Drug therapy of muscle spasm : centrally acting muscle relaxants -- Drugs for spasticity -- 26. Local anesthetics -- Basic pharmacology of the local anesthetics -- Properties of individual local anesthetics -- Clinical use of local anesthetics -- 27. General anesthetics -- Basic pharmacology of the inhalation anesthetics -- Properties of individual inhalation anesthetics -- Intravenous anesthetics -- 28. Opioid (narcotic) analgesics, opioid antagonists, and nonopioid centrally acting analgesics --Introduction to the opioids -- Basic pharmacology of the opioids -- Clinical use of opioids -- Opioid antagonists -- Nonopioid centrally acting analgesics -- 29. Pain management in patients with cancer -- Pathophysiology of pain -- Management strategy -- Assessment and ongoing evaluation -- Drug therapy -- Nondrug therapy -- Pain management in special populations -- patient education -- JCAHO pain management standards

30. Drugs for headache -- Migraine headache 1 : characteristics and overview of treatment -- Migraine headache 2 : abortive therapy -- Migraine headache 3 : preventive therapy -- Cluster headaches -- Tension[type headache -- Psychotherapeutic drugs -- 31. Antipsychotic agents and their use in schizophrenia -- Schizophrenia : clinical presentation and etiology-- Conventional antipsychotic agents 1 : group properties -- Conventional antipsychotic agents 2 : properties of individual agents -- Atypical antipsychotic agents -- Management of schizophrenia -- 32. Antidepressants -- Major depression : clinical features, pathogenesis, and treatment modalities -- Suicide risk with antidepressant drugs -- Tricyclic antidepressants -- Selective serotonin reuptake inhibitors (SSRIs) -- Serotonin/norepinephrine reuptake inhibitors (S/NRIs) -- Monoamine oxidase inhibitors (MAOIs) -- Atypical antidepressants -- Electroconvulsive therapy -- Vagus nerve stimulation -- 33. Drugs for bipolar disorder -- Characteristics of bipolar disorder -- Treatment of bipolar disorder -- Mood-stabilizing drugs -- Antipsychotic drugs -- 34. Sedative-hypnotic drugs -- Benzodiazepines -- Benzodiazepine-like drugs -- Ramelteon : a melatonin agonist -- Barbiturates -- Miscellaneous sedative-hypnotics -- Management of transient insomnia

35. Management of anxiety disorders -- Generalization anxiety disorder -- Panic disorder -- Obsessive-compulsive disorder -- Social anxiety disorder (social phobia) -- Post-traumatic stress disorder -- 36. Central nervous system stimulants and attention-deficit/hyperactivity disorder -- Amphetamines -- Methylphenidate and dexmethylphenidate -- Methylxanthines -- Miscellaneous CNS stimulants -- Attention-deficit/hyperactivity disorder -- Drug abuse -- 37. Drug abuse 1 : basic considerations -- Definitions -- Diagnostic criteria for substance abuse and substance dependence -- Factors that contribute to drug abuse -- neurobiology of addiction -- Principles of addiction treatment -- The Controlled Substance Act -- 38. Drug abuse 2 : alcohol -- Basic pharmacology of alcohol -- Alcohol abuse -- Drugs employed in alcohol abuse treatment -- 39. Drug abuse 3 : major drugs of abuse (other than alcohol) -- Heroin and other opioids -- General CNS depressants -- Psychostimulants -- Marijuana and related preparations -- Psychedelics -- 3, 4-methylenedioxymethamphetamine (MDMA, Ecstasy) -- Phencyclidine -- Inhalants -- Nicotine and smoking -- Anabolic steroids

[pt]. 6. Drugs that affect fluid and electrolyte balance -- 40. Diuretics -- Review of renal anatomy and physiology -- Introduction to diuretics -- High-ceiling (loop) diuretics -- Thiazides and related diuretics -- Thiazides and related diuretics -- Potassium-sparing diuretics -- Osmotic diuretics -- 41. Agents affecting the volume and ion content of body fluids -- Disorders of fluid volume and osmolality -- Acid-base disturbances -- Potassium imbalances -- Magnesium imbalances -- [pt]. 7. Drugs that affect the heart, blood vessels, and blood -- 42. Review of hemodynamics -- Overview of the circulatory system -- Regulation of cardiac output -- Regulation of arterial pressure -- 43. Drugs acting on the renin-angiotensin-aldosterone system -- Physiology of the renin-angiotensin-aldosterone system -- Angiotensin-converting enzyme inhibitors -- Angiotensin 2 receptor blockers -- Aldosterone antagonists -- 44. Calcium channel blockers -- Calcium channels : physiologic functions and consequences of blockade -- Calcium channel blockers : classification and sites of action -- Verapamil and diltiazem : agents that act on vascular smooth muscle and the heart -- Dihydropyridines : agents that act mainly on vascular smooth muscle

45. Vasodilators -- Basic concepts invasodilator pharmacology -- Pharmacology of individual vasodilators -- 46. Drugs for hypertension -- Classification of blood pressure -- Types of hypertension -- Consequences of hypertension -- Management of chronic hypertension 1 : basic considerations -- Management of chronic hypertension 2 : lifestyle modifications -- Management of chronic hypertension 3 : drug therapy -- Drugs for hypertensive emergencies -- Drugs for hypertensive disorders of pregnancy -- 47. Drugs for heart failure -- Pathophysiology of heart failure -- Overview of drugs used to treat heart failure -- Cardiac (digitalis) glycosides -- Management of heart failure -- 48. Antidysrhythmic drugs -- Electrical properties of the heart -- Generation of dysrhythmias -- Classification of antidysrhythmic drugs -- Prodysrhythmic effects of antidysrhythmic drugs -- Overview of common dysrhythmias and their treatment -- Class 1 : sodium channel blockers -- Class 2 : beta blockers -- Class 3 : potassium channel blockers (drugs that delay repolarization) -- Class 4 : calcium channel blockers -- Other antidysrhythmic drugs -- Principles of antidysrhythmic drug therapy -- Nondrug treatment of dysrhythmias

49. Prophylaxis of coronary heart disease : drugs that lower LDL cholesterol levels -- Cholesterol -- Plasma lipoproteins -- Role of LDL cholesterol in atherosclerosis -- Detection, evaluation, and treatment of high cholesterol : recommendations from ATP 3 -- Drugs and other products used to alter plasma lipid levels -- 50. Drugs for angina pectoris -- Determinants of cardiac oxygen demand and oxygen supply -- Angina pectoris : pathophysiology and treatment strategy -- Organic nitrates -- Beta blockers -- Calcium channel blockers -- Revascularization therapy : CABG and PCI -- Summary of treatment measures -- 51. Anticoagulant, antiplatelet, and thrombolytic drugs -- Physiology and pathophysiology of coagulation -- Overview of drugs used to treat thromboembolic disorders -- Parenteral anticoagulants 1 : heparin and related drugs -- Parenteral anticoagulants 2 : direct thrombin inhibitors -- Warfarin, and oral anticoagulant -- Antiplatelet drugs -- Thrombolytic drugs -- 52. Management of ST-elevation myocardial infarction -- Pathophysiology of STEMI -- Diagnosis of STEMI -- Management of STEMI -- Complications of STEMI -- Secondary prevention of STEMI -- 53. Drugs for hemophilia -- Basic considerations -- Preparations used to treat hemophilia -- 53. Drugs for deficiency anemias -- Red blood cell development -- Iron deficiency -- Vitamin B₁₂ deficiency -- Folic acid defficiency -- 55. Hematopoietic growth factors -- Erythropoietic growth factors -- Luekopoietic growth factors -- Thrombopoietic growth factor

[pt]. 8. Drugs for endocrine disorders -- 56. Drugs for diabetes mellitus -- Diabetes mellitus : overview of the disease and its treatment -- Insulin 1 : physiology-- Insulin 2 : preparations and administration -- Insulin 3 : therapeutic use -- Oral hypoglycemics for type 2 diabetes -- New injectable drugs for diabetes -- Diabetic ketoacidosis -- Glucagon for insulin overdose -- 57. Drugs for thyroid disorders -- Thyroid physiology -- Thyroid function tests -- Thyroid pathophysiology -- Thyroid hormone preparations for hypothyroidism -- Drugs for hyperthyroidism -- 58. Drugs related to hypothalamic and pituitary function -- Overview of hypothalamic and pituitary endocrinology -- Growth hormone -- Prolactin -- Thyrotropin -- Corticotropin -- Gonadotropins -- Antidiuretic hormone -- Oxytoxin -- Drugs related to hypothalamic function -- 59. Drugs for disorders of the adrenal cortex -- Physiology of the adrenocortical hormones -- Pathophysiology of the adrenocortical hormones -- Agents for replacement therapy in adrenocortical insufficiency -- Agents for diagnostic testing of adrenocortical function -- Inhibitors of corticosteroid synthesis

[pt]. 9. Women's health -- 60. Estrogens and progestins : basic pharmacology and noncontraceptive applications -- The menstrual cycle -- Estrogens -- Selective estrogen receptor modulators (SERMs) -- Progestins -- Menopausal hormone therapy -- 61. Birth control -- Effectiveness and safety of birth control methods -- Selecting a birth control method -- Oral contraceptives -- Combination contraceptives with novel delivery systems -- Long-acting contraceptives -- Spermicides -- Barrier devices -- Drugs for medical abortion -- 62. Drug therapy of infertility -- Infertility : causes and treatment strategies -- Drugs used to treat female infertility -- 63. Drugs that affect uterine function -- Uterine relaxants (tocolytics) and their use in preterm labor -- Uterine stimulants (oxytocicis) -- Drugs used to promote cervical ripening -- [pt]. 10. Men's health -- 64. Androgens -- Testosterone -- Clinical pharmacology of the androgens -- Androgen (anabolic steroid) abuse by athletes -- 65. Drugs for erectile dysfunction and benign prostatic hyperplasia -- Erectile dysfunction -- Benign prostatic hyperplasia

[pt.] 11. Anti-inflammartory, antiallergic, and immunologic drugs -- 66. Review of the immune system -- Introduction to the immune system -- Antibody-mediated (humoral) immunity -- Cell-mediated immunity -- 67. Childhood immunization -- General considerations -- Target diseases -- Specific vaccines and toxoids -- 68. Immunosuppressants -- Calcineurin inhibitors -- Sirlimus -- Glucocorticoids -- Cytotoxic drugs -- Antibodies -- 69. Antihistamines -- Histamine -- The two types of antihistamines : H₁ antagonists and H₂ antagonists -- H₁ antagonists 1 : basic pharmacology -- H₁ antagonists 2 : preparations -- 70. Cyclooxygenase inhibitors : nonsteroidal anti-inflammatory drugs and acetaminophen -- Mechanism of action -- Classificationod cyclooxygenase inhibitors -- First-generation NSAIDs -- Second-generation NSAIDs (COX-2 inhibitors, coxibs) -- Acetaminophen -- 71. Glucocorticoids in nonendocrine diseases -- Review of glucocorticoid physiology -- Pharmacology of the glucocorticoids -- [pt]. 12. Drugs for bone and joint disorders -- 72. Drug therapy of rheumatoid arthritis and gout -- Drug therapy of rheumatoid arthritis -- Drug therapy of gout -- 73. Drugs affecting calcium levels and bone mineralization -- Calcium physiology -- Calcium-related pathophysiology-- Drugs for disorders involving calcium -- Osteoporosis

[pt]. 13. Respiratory tract drugs -- 74. Drugs for asthma -- Pathophysiology of asthma -- Overview of drugs for asthma -- Administration of drugs by inhalation -- Beta₂-adrenergic agonists -- Glucocorticoids -- Glucocorticoid/Beta₂ agonist combination -- Cromolyn -- Nedocromil -- Methylxanthines -- Anticholinergic drugs -- Leukotriene modifiers -- Omalizumab -- Management of asthma -- 75. Drugs for allergic rhinitis, cough, and colds -- Drugs for allergic rhinitis -- Drugs for cough -- Cold remedies : combination preparations -- [pt]. 14. Gastrointestinal drugs -- 76. Drugs for peptic ulcer disease -- 77. Laxatives -- 78. Other gastrointestinal drugs -- Antiemetics -- Drugs for motion sickness -- Antidiarrheal agents -- Drugs for irritable bowel syndrome -- Drugs for inflammatory bowel disease -- Prokinetic agents -- Palifermin -- Pancreatic enzymes -- Drugs used to dissolve gallstones -- Anorectal preparations -- 15. Nutrition -- 79. Vitamins -- General considerations -- Fat-soluble vitamins -- Water-soluble vitamins -- 80. Enteral and parenteral nutrition -- Enteral nutritional therapy -- Parenteral nutritional therapy -- Drugs for obesity -- Assessment of obesity-related health risk -- Overview of obesity treatment -- Weight-loss drugs approved for long-term use -- Miscellaneous appetite suppressants -- Investigational weight-loss drugs -- Calorie-saving foods

[pt]. 16. Chemotherapy of infectious diseases -- 82. Basic principles of antimicrobial therapy -- Selective toxicity -- Classification of antimicrobial drugs -- Acquired resistance to antimicrobial drugs -- Selection of antibiotics -- Host factors that modify drug choice, route of administration, or dosage -- Dosage size and duration of treatment -- Therapy with antibiotic combinations -- Prophylactic use of antimicrobial drugs -- Misuses of antimicrobial drugs -- Monitoring antimicrobial therapy -- 83. Drugs that weaken the bacterial cell wall 1 : penicillins -- Introduction to the penicillins -- Properties of individual penicillins -- 84. Drugs that weaken the bacterial cell wall 2 : cephalosporins, carbapenems, vancomycin, aztreonam, teicoplanin, and fosfomycin -- Cephalosporins -- Carbapenems -- Other inhibitors of cell wall synthesis -- 85. Bacteriostatic inhibitors of protein synthesis : tetracyclines, macrolides and others -- Tetracyclines -- Macrolides -- Other bacteriostatic inhibitors of protein synthesis -- 86. Aminoglycosides : bactericidal inhibitors of protein synthesis -- Basic pharmacology of the aminoglycosides -- 87. Sulfonamides and trimethoprim -- Sulfonamides -- Trimethoprim -- Trimethoprim/sulfamethoxazole -- 88. Drug therapy of urinary tract infections -- Organisms that cause urinary tract infections -- Specific urinary tract infections and their treatment -- Urinary tract antiseptics

89. Antimycobacterial agents : drugs for tuberculosis, leprosy, and mycobacterium avium complex infection -- Tuberculosis 1 : clinical considerations -- Tuberculosis 2 : pharmacology of individual antituberculosis drugs -- Drugs for leprosy (Hansen's disease) -- Drugs for mycobacterium avium complex infection -- 90. Miscellaneous antibacterial drugs : fluoroquinolones, metronidazole, daptomycin, rifampin, bacitracin, and polymyxins -- Fluoroquinolones -- Additional antibacterial drugs -- 91. Antifungal agents -- Drugs for systemic mycoses -- Drugs for superficial mycoses -- 92. Antiviral agents 1 : drugs for non-HIV viral infections -- Drugs for infection with herpes simplex viruses and varicella-zoster virus -- Drugs for cytomegalovirus infection -- Drugs for hepatitis -- Drugs for influenza -- Drugs for respiratory syncytial virus infection -- 93. Antiviral agents 2 : drugs for HIV infection and related opportunistic infections -- Pathophysiology -- Classification of antiretroviral drugs -- Nucleoside/nucleotide reverse transcriptase inhibitors -- Non-nucleoside reverse transcriptase inhibitors -- Protease inhibitors -- Enfuvirtide, an HIV fusion inhibitor -- Management of HIV infection -- Prophylaxis and treatment of opportunistic infections -- HIV vaccines -- Keeping current

94. Drug therapy of sexually transmitted diseases -- Chlamydia trachomatis infections -- Gonococcal infections -- Nongonococcal urethritis -- Pelvic inflammatory disease -- Acute epididymitis -- Syphilis -- Acquired immunodeficiency syndrome -- Chancroid -- Trichomoniasis -- Bacterial vaginosis -- Herpes simplex virus infections -- Genital and anal warts (condylomata acuminata) -- Proctitis -- 95. Antiseptics and disinfectants -- General considerations -- Properties of individual antiseptics and disinfectants -- Hand hygiene for healthcare workers -- [pt]. 17. Chemotherapy of parasitic diseases -- 96. Anthelmintics -- Classification of parasitic worms -- Helminthic infestations -- Drugs of choice for helminthiasis -- 97. Antiprotozoal drugs 1: antimalarial agents -- Life cycle of the malaria parasite -- Types of malaria -- Principles of antimalarial therapy -- Pharmacology of the major antimalarial drugs -- 98. Antiprotozoal drugs 2 : miscellaneous agents -- Protozoal infections -- Drugs of choice for protozoal infections -- 99. Ectoparasiticides -- Ectoparasitic infestations -- Pharmacology of ectoparasiticides

[pt]. 18. Cancer chemotherapy -- 100. Basic principles of cancer chemotherapy -- What is cancer? -- The growth fraction and its relationship to chemotherapy -- Obstacles to successful chemotherapy -- Strategies for achieving maximum benefits from chemotherapy -- Major toxicities of chemotherapeutic drugs -- Making the decision to treat -- Looking ahead -- 101. Anticancer drugs 1: cytotoxic agents -- Introduction to the cytotoxic anticancer drugs -- Alkylating agents -- Platinum compounds -- Antimetabolites -- Antitumor antibiotics -- Mitotic inhibitors -- Mitotic inhibitors -- Topoisomerase inhibitors -- Miscellaneous cytotoxic drugs -- 102. Anticancer drugs 2 : hormonal agents, biologic response modifiers, and targeted drugs -- Glucocorticoids -- Drugs for prostate cancer -- Drugs for breast cancer -- Biologic response modifiers : immunostimulants -- Targeted drugs -- [pt]. 19. Additional important drugs -- 103. Drugs for the eye -- Drugs for glaucoma -- Cycloplegics and mydriatics -- Drugs for allergic conjunctivitis -- Drugs for age-related macular degeneration -- Additional ophthalmic drugs

104. Drugs for the skin -- Anatomy of the skin -- Topical glucocorticoids -- Keratolytic agents -- Acne -- Sunscreens -- Psoriasis -- Other dermatologic drugs -- 105. Drugs for the ear -- Anatomy of the ear -- Otitis media and its management -- Otitis externa and its management -- 106. Miscellaneous noteworthy drugs -- Drugs for pulmonary arterial hypertension -- Drotrecogin Alfa (activated) for severe sepsis -- Drugs for neonatal respiratory distress syndrome -- Drugs for cystic fibrosis -- Drugs for sickle cell anemia -- Drugs for hyperuicemia caused by cancer chemotherapy -- Gamma-hydroxybutyrate for cataplexy in patients with narcolepsy -- Riluzole for amyotrophic lateral sclerosis -- [pt]. 20. Alternative therapy -- 107. Herbal supplements -- Limited regulation : the Dietary Supplement Health and Education Act -- Adverse interactions with conventional drugs -- Oral formulations -- Standardization of herbal products -- Dosage -- Some commonly used medicinal herbs

[pt]. 21. Toxicology -- 108. Management of poisoning -- Fundamentals of treatment -- Drugs and procedures used to minimize poison absorption -- Drugs and procedures used for poison removal -- Specific antidotes -- Poison control centers -- 109. Potential weapons of biologic, radiologic, and chemical terrorism -- Bacteria and viruses -- Biotoxins -- Chemical weapons -- Radiologic weapons -- Appendixes -- A. Adult immunization -- B. Guide to gender-related drugs -- C. Pronunciation of generic drug names -- D. Weights and measures -- E. Normal laboratory values -- F. Commonly used abbreviations -- G. Techniques of drug administration -- H. Poison Control Centers in the United States -- I. Canadian drug information -- J. Major drug classes and their prototypes -- K. Very new drugs and important new formulations of older drugs

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